Synthesis and Pharmacological Significance of Isoxazoline Derivatives: A Mini review

Abstract

Five-membered cyclic compound that contains (C=N–O) bond, like isoxazoline having bioorganic and pharmacological importance is considered as useful transformation intermediate to a large number of bioactive molecules. It is well known from scientific literatures that this class of hetero-compounds has biological activities. So, thisdiscussed the synthetic methods of these building blocks targeting bioactive molecule containing isoxazoline ring with advanced and varied medical applications. A large number of research and review studies describe new synthesis pathways of isoxazolines derivatives would represent a promising matrix for the further development of the isoxazoline core which could be a leading core for future developments to obtain safer and more effective therapies.