Study the possible role of CMV and EBV infections to initiate high blood pressure in some groups of hypertensive Iraqi patients

Abstract

The main purposes of this study were to find out the possible correlation of CMV & EBV infections with high blood pressure initiation in some groups of hypertensive Iraqi patients, also to determine the relationship of between EBV & CMV infections with some clinico – pathological factors which were involved in this study. The present study was designed as a prospective research with (90) serum samples as (45) specimens from hypertensive patients (cases) and another (45) specimens from individuals with normal blood pressure (controls), collected from Baghdad teaching hospital & teaching laboratories \ Medical city \ Baghdad, from the period of March (2015) to April (2015). All samples had been subjected into ELISA test for CMV IgG & EA EBV IgG detection in private laboratory , from the period of 1st – 8th of April (2015). Statistically significant differences detected in the presence of IgG to CMV (p = 0.006 ) and EBV-EA IgG (p= 0.01) regarding to the negative results of selected study groups. According to the history of heart diseases it was with high significant difference (p= 0.000) regarding to the CMV IgG positive results comparing with the presence of EA EBV IgG (p= 0.084). Interestingly, the positive results of CMV IgG & EA EBV IgG were associated with hypertension progression. Finally, the EBV & CMV infection maybe play a significant role in the increasing of the blood pressure as a suitable co-factors.