Effect of Black seeds (Nigella Sativa L. ) Oil On Low Density Lipoprotein In Albino Rats

Abstract

In this study was to investigate the effect of black seed oil on the blood level of low density lipoprotein ( LDL ) in albino male rats . This study was done for 60 days on 40 mature albino male rats , divided into two groups ( control and treated ) . Animals of both groups were fed on common rats diet for 60 days , 2% of cholesterol was added on fed of treated group. At a day 30 of experiment , the animals were given daily oral dose of 500mg/kg body weight of oil extract of Black seeds by oral lavage. The statistical analysis in treated group showed a significant increase ( P< 0.05 ) in LDL – cholesterol at days 15 and 30 and a significant decrease at 45 and 60 days of the experiment when compared with control group