Evaluate Of Tumor Necrosis Factor - Α and Interleukin-10 of a Sample of Pregnant Women in Diyala Province During The Three Stages of Pregnancy

Abstract

This study was aimed to evaluate the immunological role of the tumor necrosis factor - alpha and Interleukin- 10 in some sample of pregnant women during three stages in Diyala province. A total of 90 blood samples were collected from pregnant women, also 30 blood samples were collected from non-pregnant apparently healthy women as a control group during the period (1/2015/10 to 1/2/2016) from the Al-Batool Teaching hospital for Gynecology and Children. The results showed that the mean age for pregnant group was 25.94±6.12 year, While for control group was 27.03±6.34 year a additionally the pregnant women group. Pregnant women's group was divided into three stages (each stage included 30 blood sample). On the other hand the results of this study showed a significant decrease (p≤0.001) in the TNF-α level in pregnant women compared to the control group with highly significant differences (p≤ 0.001) through three periods of pregnancy. Also, results revealed a significant increase (p≤ 0.001) at the level of IL-10 in pregnant women compared to the control group with highly significant differences (p≤0.001) in the level of IL-10 during the three stages of pregnancy. Shows through a these results that interleukin - 10 was his a positive role in maintaining pregnancy, while notes of tumor necrosis factor alpha negative role in the process of pregnancy.