Study of Some immunological parameters in Patients with Molluscum Contagiosum

Abstract

The aims of the study to assess the immune status of patients infected with molluscum contagiosum through the measurement of the level of immunoglobulin (IgG,IgM) and the level of complement components especially (C3,C4) by radial immune diffusion assay. The present study was conducted on the period from1 November 2013 to 30 April ,of 2014 in outpatient clinic of Baquba Teaching Hospital . 75 patients were diagnosed with clinical lesions of MCV on different areas of the body, age of patients ranged from(2-50 years) including 40(53.3%) males and 35(46.7%) females .The control were 26.6±15.4 years (range from 2-50 years), 8 (53.3%) of them were males and 7(46.7%) females. After the examination by single radial immune diffusion The results showed the patients were equal or less than 16 years, 24 (32%) from 17-30 years, 19 (25.3%) from 31-45 years and 12 (16%) above 45 years and 40(53.3%) males and 35(46.7%) females, no static significant difference showed between the MCV infection and either the sex or age . The mean±SD of IgM in patients were 1946.6±825.6 mg/dl while in control were 140.1±68.7mg/dl This result is highly significant which indicates that patients with MC had higher level of IgM than control In contrast, patients had lower levels of IgG than control, The mean±SD of IgG in patient were 221.9±96.7mg/dl while in control were 1229.9±299.7mg/dl. This result is highly significant.