EFFECT OF THE-CAMEL'S MILK ON ENZYMES AST, ALT AND ALP IN LIVER OF INDUCED DIABETIC RATS

Abstract

The aim of this study was to determine the impact of she-camel's milk on the activity of liver enzymes, Aspartate amino transaminase (AST), Alanine amino transaminase (ALT) and alkaline phosphatase (ALP). Healthy and alloxan- induced diabetic Sprague-Dawley rats were used as a model for this study. Rats were divided into seven groups (six rats each). They were, healthy control group, diabetic control group and five diabetic groups fed on raw, refrigerated, frozen, pasteurized and sterilized milk, respectively. At the end of the experiment 28 days, results revealed a significant decrease (p<0.05) in liver enzymes activity (AST, ALT and ALP) for diabetic rats fed on raw, refrigerated, frozen and pasteurized milk compared with control diabetic group, but therapeutic effect of milk was lost after sterilization. It was concluded that camel's milk played a positive role in improving the activity of liver enzymes in diabetic rats.