Effect of Coca Cola Consumption on Urinary Crystals Formation and Some Blood Biochemical Parameters

Abstract

Coca cola consumption is widely distributed in recent years, therefore the study aimed to detect the side effects of coca cola intake on urinary crystals formation and some blood biochemical parameters including serum total calcium, ionized calcium, phosphorus ,uric acid and albumin. Blood and urine samples were collected from healthy volunteers who are divided into three groups :group 1 who drink 1 can (200ml) coca cola daily. Group 2 who drink 2 can or more (400ml) coca cola daily. These results compared with control( group 3) who didn't drink soft beverages . All parameters were determined in blood samples using spectrophotometer while urine samples examined under microscope. The results revealed significant (p<0.01 ) increase in serum phosphorus ,albumin and uric acid in group 1and 2 compared to control group and significant decrease in serum total, corrected and ionized calcium in group 2 compared to control group. When compare between group1 and 2 the results revealed significant differences in serum total ,corrected ,ionized calcium and uric acid .Urine examination results appeared 39.1% of uric acid crystal and 30.4 % of amorphous urate crystals in group 1 while in group 2 drinking coca cola contribute to increased combined crystal formation which recorded uric acid with amorphus urate crystals 30% followed 15% of each Calcium oxalate with triple phosphate and Uric acid with triple phosphate. Conclusion: drinking coca cola in large quantities for long period effect ionized calcium and may lead to osteoporosis, kidney stone formation and decline in kidney function.