Synthesis and Biological Activity Evolution of 5-amino-1,3,4-thiadiazole- 2- thiol Compound and Some Derivatives

Please use this identifier to cite or link to this item: http://148.72.244.84/xmlui/handle/xmlui/6765

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DC Field	Value	Language
dc.contributor.author	Hussein-R-hammod* Khaled matne - M- * Wassan –B- Ali**	-
dc.date.accessioned	2023-10-23T19:13:39Z	-
dc.date.available	2023-10-23T19:13:39Z	-
dc.date.issued	2016	-
dc.identifier.issn	2222-8373	-
dc.identifier.uri	http://148.72.244.84:8080/xmlui/handle/xmlui/6765	-
dc.description.abstract	In this work , new of 5-amino-1,3,4-thiadiazole- 2-thiol derivatives were synthesized (S1- S19), through the reaction of 5-amino-1,3,4-thiadiazole- 2-thiol with p-hydroxy acetophenone to form azo dyes (S2), Chalcones were synthesized by reaction of compound (S2) with different aromatic aldehyde(S3-S6). Compounds (S7-S17) were finally synthesized by ring closure by hydrazine and some hydrazine derivatives . The newly synthesized compounds were confirmed by FT-IR-spectra and H1-NMR, and they showed good agreement with the proposed structures. Also the biological activity of some of the test compounds were investigated in vitro, against some bacterial.	en_US
dc.description.sponsorship	https://djps.uodiyala.edu.iq/	en_US
dc.language.iso	en	en_US
dc.publisher	University of Diyala	en_US
dc.subject	Key words: 5-amino-1,3,4-thiadiazole- 2-thiol , azo dyes , chalcones , ring quinary chalcones.	en_US
dc.title	Synthesis and Biological Activity Evolution of 5-amino-1,3,4-thiadiazole- 2- thiol Compound and Some Derivatives	en_US
dc.type	Article	en_US
Appears in Collections:	مجلة ديالى للعلوم الاكاديمية / Academic Science Journal (Acad. Sci. J.)

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