Estimate of gamma-glutamyl transferase enzyme activity and study of some biochemical changes in serum of patients with inflammation gallbladder(Cholecystitis)

Abstract

The study aimed to measure the activity of gamma-glutamyl transferase enzyme and some biochemical parameters in serum of patients with inflammation gallbladder in Baqubah Teaching Hospital for the period (12-3-2015 to 23/05/2015). they study included 100 case patints with inflammation gallbladder of females. also it included a study on (50) samples of Healthy females (control) as comparison group.The results showed a significant increase in the enzyme gamma-glutamyl transferase activity in patients with level of probability P≤ 0.01 compared with the control, where the activity of the enzyme gamma-glutamyl transferase rate (126.58 ± 33.44UI / L) in the serum of patients with inflammation gallbladder and (11.25 ± 4.88 UI / L) in the control group. the results showed a significant increase in the rate of AST and ALP enzymes activity in serum of patients compared to the control. While the results showed no significant difference in total protein concentration in the serum of patients and control.we can get these samples of blood from surgical unit in Baqubah Teaching Hospital.