Evaluation of the activity of chemical components of Calvatia craniformis mushroom in treatment of Candidal vaginitis in Khalis city women in vitro

Abstract

Candidal vaginitis is a fungal disease caused by yeast fungi resulting in vaginal discharge , irritation , and itching . This study aims to evaluate the efficacy of the chemical components of Calvatia craniformis mushroom powder in treatment of Candidal vaginitis in women in vitro . Three different concentrations of ethanolic extract were prepered from C.craniformis mushroom powder ( 1 , 0.8 , 0.6 ) % and used as comparison with common antifungal drugs as fluconazole and nystatin . Statistical analysis of values is revealed significant effect ( p<0.05) ) of two concentrations ( 1 , 0.8 ) % ; this result reflected by values of the diameter of zone of inhibition were be ( 2 , 1.6 ) centimeter when were compared with the effect of fluconazole and nystatin which be ( 0.9 , 0.8) centimeter respectively .