Effect of Date Palm Pollen Suspension on Ovarian Function and Fertility in Adult Female Rats Exposed to Lead Acetate

Abstract

This study present the effects of Date Palm Pollen grains (DPP) (phoenix dactylifera) on ovary function and fertility in adult female rats exposed to lead acetate. Forty adult female albino rats were divided randomly into four equal groups. The first control group was given orally (1 ml) distal water,(T1) group given orally 150 mg / kg .B.W. DPP ( 0.5ml),(T2) group given orally (10) mg / kg. B.W. lead acetate (1 ml) ,(T3) group given daily by oral administration of both DPP150 mg/kg B.W. and 10 mg / kg. B.W. lead acetate .all animals treated via gavages needle for 6 weeks.At the end of experiment blood were collected to determine serum LH & FSH level . Treated( T1) group showed the increase levels of LH were on significant importance at a level of < 0.05 in comparison with zero time of the same group and in comparison with control group . To contrast to treated(T1) group, the level on LH showed a significantly decrease levels in animals on treated (T2) group exposure lead acetate at a dose rate of 10 mg / kg. B.W daily . The significant decrease in LH were showed in comparison the value with that at zero day of the same group and at a time on experiment 14, 28, 42 day post exposure in comparison with control group and with (T1) group exposed to DPP. Animal on treated (T3) group exposed of both DPP at 150 mg /kg. B. W. and lead acetate 10 mg / kg. B.W. for 6 weeks didn`t show any significant changes during the experiment. Animals on( T1) group that exposed to DPP at a dose rate on 150 mg / k. B.W. for 6 weeks showed a significant increase FSH level in serum of exposed animal in comparison with zero time of the same group and in comparison with contrl group . While those on (T2) group which exposed to lead acetate at a dose rate of 10 mg / kg. B.W. for 6 weeks showed a significant decrease in FSH level in serum on day 14 and 42 following the exposure the decrease in FSH level in serum may significant in comparison with zero day of same group and with level on T1 group and control group. Animal on group T3 didn`t show any significant changes during the experiment. This study conclude that DPP has obvious improvement effect on fertility hormones of Adult female rats exposed to lead acetate.