Synthesis , characterize and biological studies of (Cr(III) ,Mn(II) ,Zn(II)and Cd(II)) complexs with Schiff-base ligand.

Abstract

The new multidentate Schiff-base ligand (2,6-bis-[(3-phenyl thiourea-imino)-methyl]- phenol) HL and its monomeric metal complexes with Cr(III) ,Mn(II) ,Zn(II)and Cd(II) are reported. The ligand HL was derived from the condensation reaction of ( 2,6-diformyl-4- methyl-phenol) with (4-phenylthiosemicarbazide) in mole ratios of 1:2 . The complexes were prepared from the reaction of the corresponding metal chloride with the ligand .The ligand and its metal complexes were characterised by spectroscopic methods (FTIR, UV-Vis,1H NMR, 13C. A.A), chloride content, conductance and melting point measurements.These studies revealed octahedral geometries for Cr(III), Mn(II), and Cd(II) complexes of general formulae [CrIII(L)Cl]Cl, [MnII(L)Cl] and [CdII (L)Cl] and five co-ordinate Zn(II) complex of general formula [ZnII(L)]Cl .Biological activity of the ligand and its metal complexes against gram positive bacterial strain Bacillus (G+) and gram negative bacteria Pseudomonase (G-) revealed that the metal complexes become less resistive to the microbial activities as compared to the free ligand.