A comparative study of the healing effects of sesame oil and TiO2nanoparticles gel on second-degree burn

Abstract

Burns, asevere form of soft tissue injury , can cause significant damage and, in extreme cases, be fatal. They also lead to considerable mental and emotional distress due to excessive scarring and skin contractures. Desp ite various treatment methods, burn care remains a challenging medical issue.In this study , titanium dioxide (TiO2) nanop articles were sy nthesized and characterized using Field Emission Scanning Electron M icroscop y (FE-SEM ), revealing p article sizes ranging from 31.52 to 69.08 nanometers.The imp act of biosy nthetic nanomaterials and sesame seed oil on burn healing in laboratory rats was investigated. The study comp ared the effects of a 1% TiO2solution and 20% sesame oil on burned skin with a control group of rats having natural skin.Fifteen rats were divided into three group s, each receiving daily treatment for 28 day s. The results indicated that the TiO2treatment significantly accelerated healing comp ared to the sesame seed oil group , which had a slower healing rate of 0.12 p oints p er day . The TiO2treatment demonstrated a marked imp rovement in healing sp eed and effectiveness