Effect of Quercetin on Asthma and Nasal Allergies as an Immunomodulator: Review

Abstract

Quercetin is a flavonoid found in nature, and is rich in antioxidants. It is recognized as an important natural substance, notable for its potent effects in modulating the immune system and its anti-inflammatory characteristics. Many fruits and vegetables, such as onions, shallots, apples, and different berries, contain quercetin. Consequently, this review aims to elucidate the function of quercetin as an immune enhancer and its significance in managing asthma and nasal allergies. A variety of research studies involving both human and animal subjects have been conducted, with ongoing investigations both in vitro and in vivo continuing until 2024. The effects of quercetin as an anti-inflammatory agent and antiasthmatic conditions, it is also linked to decreased levels of interleukin IL-4, inhibition of histamine release, and a decrease in the synthesis of pro-inflammatory cytokines and leukotrienes. Quercetin has the potential to diminish the creation of antigen-specific IgE immunoglobulin and enhance the balance between Th1 and the responses. inconclusion: the characteristics of quercetin could serve as a therapeutic approach for conditions such as asthma and nasal allergies.