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http://148.72.244.84/xmlui/handle/xmlui/2948| Title: | The Role of Biofilm Formation of Secondary Bacterial Infections in Severity of COVID-19 Patients |
| Authors: | Ahmed Farhan Hamad Zainab Mohammed Alzubaidy |
| Keywords: | COVID-19, SecondaryBacterialInfections, AntibioticsResistance, Biofilmformation. COVID-19, SecondaryBacterialInfections, AntibioticsResistance, Biofilmformation. |
| Issue Date: | 2023 |
| Publisher: | univercit of diyala |
| Citation: | https://doi.org/10.24237/ASJ.01.02.617B |
| Abstract: | ThepresentstudyincludedOnehundredandfifty-fivespecimenswerecollectedfromCOVID-19patients(maleandfemale)admittedandhospitalizedinICUafterconfirmingtheinfectionbyusingReversetranscription-polymerasechainreaction(RT-PCR)aswellasXrayandCTscanatBaqubaaTeachingHospitalfromtheperiodofthefirstofOctober2021tothefirsttoMarch2022.Thesourcesofthespecimensinclude(100)pharyngealswabsand(55)sputum.Selectiveanddifferentialmedia,microscopicexamination,biochemicaltestsandtheVitek-2compactsystemwereusedindiagnosealltheisolates.Forty-five(29%)isolatesfromatotalof155severCOVID-19patientsshowedpositivegrowthatapercentage(30%)while70%showednegativegrowth.Thepositivegrowthisolatesweredistributedas155/10(6.45%)isolatesofgram-positiveStaphylococcusaureuswereisolatedonlyfromPharyngealswabatapercentageof10(10%)andtwotypesofgram-negativeisolateswhichwas155/22(14.19%)ofPseudomonasaeruginosaand13(8.38%)Acinetobacterbaumannii,bothofthemisolatedfromPharyngealswab5(5%)and9(9%),andfromSputumwas17(30.9%),and4(7.27%)respectively.Antibioticssensitivitytestrevealedstrongresistanceagainst12antibioticsfromdifferentclasseswereusedforeachisolates,theresultsshowedthattherewasnumerousbacteriumisolateswithmultipledrugresistance(MDR)andextensivelydrugresistance(XDR)theresultsindicatedthatfromthetotal10isolatesofStaphylococcusaureusshowedresistancetoChloramphenicol(87%),Clarithromycin(85%),Trimethoprim-sulfamethoxazole(82%),Imipenem(81%),Levofloxacin(79%),Nitrofurantoin(78%),PenicillinandDoxycycline ThepresentstudyincludedOnehundredandfifty-fivespecimenswerecollectedfromCOVID-19patients(maleandfemale)admittedandhospitalizedinICUafterconfirmingtheinfectionbyusingReversetranscription-polymerasechainreaction(RT-PCR)aswellasXrayandCTscanatBaqubaaTeachingHospitalfromtheperiodofthefirstofOctober2021tothefirsttoMarch2022.Thesourcesofthespecimensinclude(100)pharyngealswabsand(55)sputum.Selectiveanddifferentialmedia,microscopicexamination,biochemicaltestsandtheVitek-2compactsystemwereusedindiagnosealltheisolates.Forty-five(29%)isolatesfromatotalof155severCOVID-19patientsshowedpositivegrowthatapercentage(30%)while70%showednegativegrowth.Thepositivegrowthisolatesweredistributedas155/10(6.45%)isolatesofgram-positiveStaphylococcusaureuswereisolatedonlyfromPharyngealswabatapercentageof10(10%)andtwotypesofgram-negativeisolateswhichwas155/22(14.19%)ofPseudomonasaeruginosaand13(8.38%)Acinetobacterbaumannii,bothofthemisolatedfromPharyngealswab5(5%)and9(9%),andfromSputumwas17(30.9%),and4(7.27%)respectively.Antibioticssensitivitytestrevealedstrongresistanceagainst12antibioticsfromdifferentclasseswereusedforeachisolates,theresultsshowedthattherewasnumerousbacteriumisolateswithmultipledrugresistance(MDR)andextensivelydrugresistance(XDR)theresultsindicatedthatfromthetotal10isolatesofStaphylococcusaureusshowedresistancetoChloramphenicol(87%),Clarithromycin(85%),Trimethoprim-sulfamethoxazole(82%),Imipenem(81%),Levofloxacin(79%),Nitrofurantoin(78%),PenicillinandDoxycycline |
| URI: | http://148.72.244.84:8080/xmlui/handle/xmlui/2948 |
| ISSN: | 2958-4612 |
| Appears in Collections: | مجلة ديالى للعلوم الاكاديمية / Academic Science Journal (Acad. Sci. J.) |
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