Evaluating the prevalence measles virus IgM antibodies for under 2 years children in Diayala governorate.

Abstract

The goal of present study was to evaluating the prevalence of measles virus (MV) immunoglobulin M antibodies in children under two year . This study was conducted from the period from 1 / 5 / 2015 to 30/ 2 / 2016. It included; Sera of 163 from children ,91(55.8%) from children aged (0-8)months and 72(44.2%) from children aged (9-23) months were collected from Al-Batool teaching Hospital. Detection of anti-measles IgM antibody was done by Enzyme – linked immunosorbent assay in the Center Public Health Laboratory. The seroprevalence of measles virus IgM obtained in this study 35(21.5%) were anti-MV IgM positive and 128(78.5%) children were anti-MV IgM negative. Additionally positivity of measles virus infection (28.2%) among children aged (0–8) months , and (12.5%) among children aged ( 9-23) months .Moreover the sero-prevalence of IgM was 5 (10%) among males and 30 (26.5%) among females. Furthermore, the prevalence of IgM 5(6.9%) among vaccinated children ,On other hand 30(32.9%) among unvaccinated children. As well as, the Positivity of IgM 12 (11.2%) in Children of mothers with vaccinated or a past history of measles, While 23 (41%) among children of mothers with unvaccinated or no a past history of measles. Finally ,the prevalence of IgM was 2(2.6%) in children who were breast feeding, but 33(37.9%) among non-breastfeeding children. In conclusion, the prevalence of anti-MV IgM was higher among aged (0–8) months. For the more, the prevalence of IgM was higher among females. Additionally prevalence its higher among unvaccinated children. While prevalence its higher among children of mothers with unvaccinated or no history of measles. Finally ,the prevalence its higher among non- breastfeeding children.