Hormonal Association between Hyperprolactinemia and Hypothyroidism In Iraqi Infertile Males

Abstract

The objective of this study is to clarified at least in part the association between hypothyroidism and hyperprolactinemia in Iraqi males which contribute to infertility .Sixty male subjects enrolled in this study.Thirty infertile males as patients group which attended AlKindey Hospital during (2010-2011).The other group consiste thirty healthy individuals as control group. The levels of serum thyroid stimulating hormone (TSH), thyroxine (T4), prolactin(PRL),testosteron(Tes),luteinizing hormone(LH) and follicle stimulating hormone (FSH) were estemated utilizing ELISA technique.The results revealed a significant increase in TSH ,PRL,Tes levels ,while a significant decrease in T4,LH,and FSH levels in infertile males comparing to control group was found.A conclusion could be drawn that elevated levels of TSH stimulates prolactin secretion ,which eventually tends to induce infertility in males by influencing spermatogensis and steriodgenesis .